Ross U H, Reinhardt M J, Berlis A
Department of Oto-Rhino-Laryngology, University of Freiburg, Germany.
J Laryngol Otol. 1995 Nov;109(11):1051-6. doi: 10.1017/s0022215100132001.
High-resolution, tympano-cochlear scintigraphy (TCS) is a useful tool for visualizing changes in labyrinthine bone metabolism in active otosclerosis in vivo. But until now, the activity patterns have mostly been rather imprecisely ascribed to the labyrinthine structures; more exactly by means of high-resolution CT (HR-CT). Experimental studies on TCS using a human temporal bone model revealed that correlative imaging of X-ray photographs and the scintigrams or superimposition with masks of the temporal bone drawn from the X-rays can facilitate the localization of small foci of about 0.5-1 mm. Clinical applications of the visualization technique, combining functional with structural images, confirmed the benefit of this method, improving the accuracy in detection and localization of focal activity enrichment of the petrous bone in cases of active otosclerosis by means of TCS.
高分辨率鼓室-耳蜗闪烁扫描术（TCS）是一种在体内观察活动性耳硬化症中迷路骨代谢变化的有用工具。但到目前为止，活动模式大多被相当不准确地归因于迷路结构；通过高分辨率CT（HR-CT）能更准确地归因。使用人类颞骨模型对TCS进行的实验研究表明，将X线照片与闪烁图进行相关成像或与从X线片中绘制的颞骨掩模叠加，可以促进对约0.5-1毫米小病灶的定位。将功能图像与结构图像相结合的可视化技术的临床应用证实了该方法的益处，通过TCS提高了在活动性耳硬化症病例中检测和定位岩骨局灶性活动增强的准确性。
