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生物信号分子的临床应用

Clinical applications of BSM.

作者信息

Nadeau R, Savard P, Gulrajani R, Cardinal R, Molin F, Pagé P

机构信息

Hôpital du Sacré-Coeur de Montréal, Department of Medicine, Canada.

出版信息

J Electrocardiol. 1995 Oct;28(4):334-5. doi: 10.1016/s0022-0736(05)80053-6.

Abstract

Body surface mapping (BSM) has now become a feasible clinical technique, providing useful information applicable to the diagnosis of cardiac arrhythmias and their treatment by surgical and endocardial catheter ablation. In WPW patients, validation of preexcitation patterns has been obtained by computer simulation and by direct epicardial mapping at surgery. BSM pacemapping has subsequently been developed to be used during radiofrequency catheter ablation. This method has been evaluated prospectively and its predictive accuracy assessed. The recognition of two distinct BSM patterns in idiopathic ventricular tachycardia, has led to the application of successful pacemapping for radiofrequency catheter ablation. The use of a realistic tri-dimensional heart-torso computer model has shown that specific sites of endocardial stimulation are related to distinct thoracic map patterns.

摘要

体表标测(BSM)现已成为一种可行的临床技术,可提供适用于心律失常诊断及其通过外科手术和心内膜导管消融治疗的有用信息。在预激综合征(WPW)患者中,已通过计算机模拟和手术时直接的心外膜标测获得了预激模式的验证。随后开发了BSM起搏标测以用于射频导管消融期间。该方法已进行了前瞻性评估并评估了其预测准确性。在特发性室性心动过速中识别出两种不同的BSM模式,已导致成功应用起搏标测进行射频导管消融。使用逼真的三维心脏-躯干计算机模型表明,心内膜刺激的特定部位与不同的胸壁图模式相关。

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