C3H小鼠乳腺肿瘤病毒的主要组织相容性复合体II类I-E非依赖性传播
Major histocompatibility complex class II I-E-independent transmission of C3H mouse mammary tumor virus.
作者信息
Wrona T, Dudley J P
机构信息
Department of Microbiology, University of Texas at Austin 78712, USA.
出版信息
J Virol. 1996 Feb;70(2):1246-9. doi: 10.1128/JVI.70.2.1246-1249.1996.
Abstract
C57BL/6 mice are resistant to C3H mouse mammary tumor virus (MMTV)-induced mammary tumorigenesis and lack major histocompatibility complex class II I-E molecules that are essential for presentation of C3H superantigen to T cells. T cells are needed for transmission of milk-borne MMTV from the gut to the mammary gland. In this report, we show that infectious C3H MMTV is produced by C57BL/6 mice that nurse on C3H mothers but that virus production in the mammary gland is delayed compared with that in I-E+ mouse strains.
摘要
C57BL/6小鼠对C3H小鼠乳腺肿瘤病毒（MMTV）诱导的乳腺肿瘤发生具有抗性，并且缺乏主要组织相容性复合体II类I-E分子，而该分子对于将C3H超抗原呈递给T细胞至关重要。T细胞是乳汁传播的MMTV从肠道传递到乳腺所必需的。在本报告中，我们表明，由C3H母鼠哺育的C57BL/6小鼠会产生具有传染性的C3H MMTV，但与I-E+小鼠品系相比，乳腺中的病毒产生会延迟。
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本文引用的文献
1
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J Exp Med. 1993 Oct 1;178(4):1441-5. doi: 10.1084/jem.178.4.1441.
2
Superantigen-induced immune stimulation amplifies mouse mammary tumor virus infection and allows virus transmission.超抗原诱导的免疫刺激会放大小鼠乳腺肿瘤病毒感染并促进病毒传播。
Cell. 1993 Aug 13;74(3):529-40. doi: 10.1016/0092-8674(93)80054-i.
3
T-cell receptor repertoire selection by mouse mammary tumor viruses and MHC molecules.
Immunol Rev. 1993 Feb;131:93-115. doi: 10.1111/j.1600-065x.1993.tb01532.x.
4
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J Virol. 1994 Aug;68(8):5019-26. doi: 10.1128/JVI.68.8.5019-5026.1994.
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9
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