Masuda A, Shimamoto K, Iimura O
Second Department of Internal Medicine, Sapporo Medical University School of Medicine.
Nihon Ronen Igakkai Zasshi. 1995 Oct;32(10):648-55. doi: 10.3143/geriatrics.32.648.
A case-card survey was carried out to understand trends of hypotensive treatment in elderly in comparison with non-elderly subjects. Data were obtained from 2,897 cases including 1,422 elderly (> or = 65 years old) and 1,475 non-elderly hypertensives (< 65 years old) collected from Sapporo Medical University Hospital and related medical facilities. In the total group of 2,879 cases, frequencies of use of hypotensive drugs were as follows: Ca antagonists, 76.3%, beta-blockers, 31.4%; ACE-inhibitors, 25.1%; diuretics, 18.1; alpha 1-blockers, 10.5%; potassium sparing diuretics, 8.8%. In the elderly group, beta-blockers and ACE-inhibitors were used less frequently than in non-elderly hypertensives. On the contrary, diuretics were administered more frequently in elderly than in non-elderly subjects. Comparing the usage of hypotonics among different types of medical facilities, higher frequencies of use of beta-blockers and diuretics were observed in the university hospital than in general hospitals and private hospitals or clinics. ACE-inhibitors were used less frequently in private facilities than in the university hospital and general hospital. In summary, Ca antagonists were used most frequently in both non-elderly and elderly subjects, and in all three different types of medical facilities. Other hypotonics were used differently according to patients age. There was differences in the usage of drugs apart from Ca antagonists among the three different types of medical facilities.
开展了一项病例卡调查,以了解老年患者与非老年患者相比的降压治疗趋势。数据来自于从札幌医科大学医院及相关医疗机构收集的2897例病例,其中包括1422例老年患者(≥65岁)和1475例非老年高血压患者(<65岁)。在总共2879例病例组中,降压药物的使用频率如下:钙拮抗剂,76.3%;β受体阻滞剂,31.4%;血管紧张素转换酶抑制剂,25.1%;利尿剂,18.1%;α1受体阻滞剂,10.5%;保钾利尿剂,8.8%。在老年组中,β受体阻滞剂和血管紧张素转换酶抑制剂的使用频率低于非老年高血压患者。相反,老年患者中利尿剂的使用频率高于非老年患者。比较不同类型医疗机构中降压药的使用情况,大学医院中β受体阻滞剂和利尿剂的使用频率高于综合医院和私立医院或诊所。私立医疗机构中血管紧张素转换酶抑制剂的使用频率低于大学医院和综合医院。总之,钙拮抗剂在非老年和老年患者以及所有三种不同类型的医疗机构中使用最为频繁。其他降压药根据患者年龄的不同而使用情况各异。三种不同类型的医疗机构中,除钙拮抗剂外,药物的使用情况存在差异。