Dziewulska-Bokiniec A
Department of Oncology and Radiotherapy, Medical University of Gdańsk, Poland.
Neoplasma. 1995;42(5):285-7.
The possible association between cigarette smoking and the risk of benign breast disease (BBD) was assessed in a case-control study conducted in Gdańsk, Poland, between 1990 and 1994. The study compared 160 women with newly diagnosed BBD admitted to the Gdańsk Cancer Outpatients Clinic and 160 controls, women from outpatients clinics at the Medical University of Gdańsk. There was no convincing evidence of an association, either positive or negative, between various indicators of smoking habit (smoking status, number of cigarettes smoked per day, duration of smoking) and the risk of BBD. Slightly lower relative risks (RRs) of BBD in ex-smokers of 10 or more cigarettes per day (RR = 0.9; 95% confidence interval, CI: 0.4-2.2), and with duration of smoking > or = 20 years (RR = 0.8; 95% CI: 0.1-3.4), were also observed in current smokers (RR = 0.8; 95% CI: 0.4-1.5), and (RR = 0.8; 95% CI: 0.1-3.4), but these findings were not statistically significant.
1990年至1994年期间，在波兰格但斯克进行了一项病例对照研究，评估吸烟与良性乳腺疾病（BBD）风险之间的可能关联。该研究比较了160名新诊断为BBD并入住格但斯克癌症门诊的女性与160名对照者，这些对照者来自格但斯克医科大学门诊。没有令人信服的证据表明吸烟习惯的各种指标（吸烟状态、每日吸烟量、吸烟持续时间）与BBD风险之间存在正相关或负相关。在每天吸烟10支或更多的既往吸烟者中，BBD的相对风险（RR）略低（RR = 0.9；95%置信区间，CI：0.4 - 2.2），吸烟持续时间≥20年的既往吸烟者中，BBD的相对风险也略低（RR = 0.8；95% CI：0.1 - 3.4），当前吸烟者中同样观察到类似情况（RR = 0.8；95% CI：0.4 - 1.5），以及（RR = 0.8；95% CI：0.1 - 3.4），但这些结果在统计学上并不显著。
