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神经传导速度和不应期作为神经毒性的参数。

Nerve conduction velocity and refractory period as parameters of neurotoxicity.

作者信息

Roberts D V, Trollope I E

出版信息

Electroencephalogr Clin Neurophysiol. 1979 Mar;46(3):351-4. doi: 10.1016/0013-4694(79)90209-8.

DOI:10.1016/0013-4694(79)90209-8
PMID:85528
Abstract

The maximum conduction velocity (MCV) and minimum refractory period (MRP) were measured in rat sacral ventral and dorsal roots, and saphenous nerves. At 32 degrees C values for MCV were 81.45, 73.96 and 49.12 m/sec for the ventral and dorsal roots, and saphenous nerves respectively, with corresponding temperature coefficients of 3.9, 3.25 and 2.14 m/sec/degrees C. Values of MRP at 32 degrees C for the 3 nerve preparations were 0.63, 0.52 and 0.47 msec, with an average temperature coefficient of 0.04 msec/degrees C at 32 degrees C.

摘要

在大鼠骶部腹侧和背侧神经根以及隐神经中测量了最大传导速度(MCV)和最小不应期(MRP)。在32摄氏度时,腹侧和背侧神经根以及隐神经的MCV值分别为81.45、73.96和49.12米/秒,相应的温度系数分别为3.9、3.25和2.14米/秒/摄氏度。3种神经制剂在32摄氏度时的MRP值分别为0.63、0.52和0.47毫秒,在32摄氏度时平均温度系数为0.04毫秒/摄氏度。

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