Strauss P R, Gagiano C A, van Rensburg P H, de Wet K J, Strauss H J
Department of Psychiatry, University of the Orange Free State, Bloemfontein.
S Afr Med J. 1995 Aug;85(8):755-9.
Major depression is underdiagnosed by general practitioners, but the reasons for this are not clear. This study aimed to establish the prevalence of major depression and coexisting generalised anxiety disorder in a rural general practice in the Orange Free State. It also assessed the predictive value of a screening questionnaire for use by general practitioners. The two practitioners evaluated 858 patients over a 4-week period. Those who met the screening criteria, together with a random sample of 60 patients who did not, were re-evaluated by a registrar in psychiatry who was unaware of the findings of his colleagues. Of the patients studied, 134 (15.6%) had major depression; 59 of these (44.0%) also had coexisting generalised anxiety disorder. The general practitioners had correctly diagnosed major depression in 32 patients (3.7%) before the study started. The screening questionnaire had a 42% chance of correctly identifying a patient with depression and a 97% chance of correctly identifying a patient who did not have major depression. Both practitioners were equally capable at identifying major depression. The study confirmed both the high prevalence of depression in a rural general practice and its low identification rate. It also showed the advantage of using a screening questionnaire to alert practitioners to the possibility of depression in their patients.
全科医生对重度抑郁症的诊断不足,但原因尚不清楚。本研究旨在确定奥兰治自由邦一家农村全科诊所中重度抑郁症和并存的广泛性焦虑症的患病率。它还评估了一份供全科医生使用的筛查问卷的预测价值。这两位医生在4周内对858名患者进行了评估。符合筛查标准的患者,以及60名不符合标准的患者的随机样本,由一名不了解其同事检查结果的精神科住院医生重新进行评估。在研究的患者中,134人(15.6%)患有重度抑郁症;其中59人(44.0%)还并存广泛性焦虑症。在研究开始前,全科医生正确诊断出32名患者(3.7%)患有重度抑郁症。筛查问卷正确识别抑郁症患者的几率为42%,正确识别未患重度抑郁症患者的几率为97%。两位医生在识别重度抑郁症方面能力相当。该研究证实了农村全科诊所中抑郁症的高患病率及其低识别率。它还显示了使用筛查问卷提醒医生注意其患者患抑郁症可能性的优势。