Zajecka J M, Ross J S
Woman's Board Depression Treatment and Research Center, Rush Institute for Mental Well-Being, Rush-Presbyterian-St. Luke's Medical Center, Chicago, Ill. 60612.
J Clin Psychiatry. 1995;56 Suppl 2:10-3.
The coexistence of anxiety and depression is common and frequently poses diagnostic and treatment challenges in the clinical setting. Although precise diagnosis is important for treatment selection, it is often complicated by the shortcomings of the current classification system. Whereas some patients present with symptoms that meet the diagnostic criteria for both an anxiety disorder and major depression, others may present with "subsyndromal" symptoms of depression and/or anxiety. Epidemiologic data and a rational treatment approach to the patient with mixed anxiety and depression, depressive symptoms coexistent with "syndromal" and "subsyndromal" symptoms of generalized anxiety disorder, panic disorder, obsessive compulsive disorder, and social phobia are discussed, as well as areas of future research to examine coexisting anxiety and depression.
焦虑和抑郁并存的情况很常见，在临床环境中常常给诊断和治疗带来挑战。尽管准确诊断对于治疗方案的选择很重要，但当前分类系统的缺陷常常使其变得复杂。有些患者表现出既符合焦虑症又符合重度抑郁症诊断标准的症状，而另一些患者可能表现出抑郁和/或焦虑的“亚综合征”症状。本文讨论了混合性焦虑和抑郁患者、伴有广泛性焦虑症、惊恐障碍、强迫症和社交恐惧症的“综合征”及“亚综合征”症状并存的抑郁症状患者的流行病学数据和合理治疗方法，以及未来研究共存的焦虑和抑郁的领域。
