Gioseffi O N, Nucifora E, Fantl D, Dufour C, Milone J, Di Paolo H
Hospital Nacional Profesor Alejandro Posadas, Prov. de Buenos Aires, Argentina.
Sangre (Barc). 1995 Oct;40(5):421-4.
Human T-cell lymphotropic virus type I (HTLV-I) is associated with adult T-cell leukaemia/lymphoma (ATLL) and tropical spastic paraparesis (TSP/HAM) in endemic and non-endemic areas. Serological studies have shown that HTLV-I is prevalent in some Latin American countries such as Brasil, Chile, Colombia, Perú and Uruguay. We describe here the clinical and laboratory features of five cases of ATLL diagnosed in Argentina. All patients (4 males, 1 female; median age 48.2 years) were of caucasian origin; 4 born in Argentina and 1 in Chile. High risk factors for HTLV-I infection were not apparent in Argentina patients, whereas the Chilean resident, who was a promiscuous heterosexual, travelled through Chile frequently. Positive results for antibodies to HTLV-I were detected in all five cases and in some of their relatives. This report suggests that HTLV-I infection may be endemic in, Argentina where TSP has also been described.
人类嗜T细胞病毒I型（HTLV-I）在流行地区和非流行地区均与成人T细胞白血病/淋巴瘤（ATLL）及热带痉挛性截瘫（TSP/HAM）相关。血清学研究表明，HTLV-I在一些拉丁美洲国家如巴西、智利、哥伦比亚、秘鲁和乌拉圭流行。我们在此描述在阿根廷诊断的5例ATLL患者的临床和实验室特征。所有患者（4例男性，1例女性；中位年龄48.2岁）均为白种人；4例出生于阿根廷，1例出生于智利。阿根廷患者中HTLV-I感染的高危因素不明显，而那名智利居民是一名杂乱的异性恋者，经常在智利各地旅行。所有5例患者及其部分亲属的HTLV-I抗体检测结果均为阳性。本报告提示，HTLV-I感染在阿根廷可能为地方性流行，该国也有TSP的相关报道。
