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[急性颅脑创伤动态过程中脑组织生物能量代谢过程的状态]

[Status of bioenergetic processes in brain tissue in dynamics of acute cranio-cerebral trauma].

作者信息

Novikov V E, Kozlov N B, Kovaleva L A

出版信息

Vopr Med Khim. 1995 Sep-Oct;41(5):26-8.

PMID:8553621
Abstract

Acute brain injury was simulated in rat experiments. Great changes were revealed in carbohydrate and energy metabolism over the course of the posttraumatic period. The changes are the most pronounced 1 day after injury and they showed deep energy deficiency in brain tissue and precede the development of and greatly contribute to the pathogenesis of many posttraumatic disorders, including brain edema-swelling.

摘要

在大鼠实验中模拟急性脑损伤。在创伤后阶段,碳水化合物和能量代谢出现了巨大变化。这些变化在损伤后1天最为明显,表现为脑组织深度能量缺乏,先于许多创伤后疾病的发生,并在其发病机制中起重要作用,包括脑水肿肿胀。

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