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二硫化碳中毒影响下的血清和尿液氨基酸模式

Serum and urine amino acid pattern under the effect of carbon disulfide intoxication.

作者信息

El-Dessouky E A, Hawary M F, El-Shobaki F A, El-Hawary Z, Massoud A A

出版信息

Z Ernahrungswiss. 1977 Mar;16(1):31-8. doi: 10.1007/BF02021209.

DOI:10.1007/BF02021209
PMID:855380
Abstract

The effect of carbon disulphide intoxication on amino acid pattern was studied. Five groups of rats were treated with carbon disulphide through intramuscular injection of 0.05 ml CS2 in 0.2 mg olive oil/rat/day. A number of rats were sacrificed after receiving 10, 20, 30, 40, and 50 injections. As a result of intoxication, a state of hypoaminoacidemia and hyperaminoacidurea affected all the amino acids investigated, but to variable extent. Of value to add that stoppage of carbon disulphide leads to improvement of the amino-acid pattern in group six, compared to the other groups.

摘要

研究了二硫化碳中毒对氨基酸模式的影响。将五组大鼠通过肌肉注射0.05 ml二硫化碳(溶于0.2 mg橄榄油/大鼠/天)进行处理。在接受10、20、30、40和50次注射后处死若干大鼠。中毒导致的低氨基酸血症和高氨基酸尿症状态影响了所有研究的氨基酸,但程度各不相同。值得补充的是,与其他组相比,停止二硫化碳处理会使第六组的氨基酸模式得到改善。

相似文献

1
Serum and urine amino acid pattern under the effect of carbon disulfide intoxication.二硫化碳中毒影响下的血清和尿液氨基酸模式
Z Ernahrungswiss. 1977 Mar;16(1):31-8. doi: 10.1007/BF02021209.
2
Metabolism of glucose and free amino acids in brain, studies with 14C-labelled glucose and butyrate in rats intoxicated with carbon disulphide.
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Serum mineral changes under the effect of carbon disulfide intoxication.二硫化碳中毒影响下的血清矿物质变化
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Effect of carbon disulphide intoxication on fecal excretion of end products of cholesterol metabolism.二硫化碳中毒对胆固醇代谢终产物粪便排泄的影响。
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The levels of the nicotinamide-adenine dinucleotides in the tissues of rabbits and rats after chronic exposure to carbon disulphide.慢性接触二硫化碳后家兔和大鼠组织中烟酰胺腺嘌呤二核苷酸的水平
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本文引用的文献

1
Biochemical mechanisms in chronic carbon disulfide poisoning.慢性二硫化碳中毒的生化机制
Am Ind Hyg Assoc J. 1959 Aug;20(4):303-23. doi: 10.1080/00028895909343722.
2
[Dithiocarbamin carbonic acids as waste products of carbon disulfide].[二硫代氨基甲酸作为二硫化碳的废弃物]
Arch Gewerbepathol Gewerbehyg. 1956;14(5):511-21.
3
[Clinical and experimental research on atherosclerosis caused by carbon disulfide].[二硫化碳所致动脉粥样硬化的临床与实验研究]
Arch Gewerbepathol Gewerbehyg. 1955;14(2):190-202.
4
[Absorption, metabolism, and action of carbon disulfide on the organism. IV. Studies on elimination of carbon disulfide in prolonged experiments].[二硫化碳对机体的吸收、代谢及作用。IV. 长期实验中关于二硫化碳消除的研究]
Prac Lek. 1953 Sep;5(4):181-91.
5
Effects of carbon disulphide on the liver of rats.二硫化碳对大鼠肝脏的影响。
Br J Ind Med. 1969 Oct;26(4):335-7. doi: 10.1136/oem.26.4.335.
6
The effect of the protein value of the diet on the neurological manifestations produced in rats by beta, beta-iminodipropionitrile.饮食中蛋白质含量对β,β-亚氨基二丙腈所致大鼠神经症状的影响。
Br J Nutr. 1967;21(2):269-74. doi: 10.1079/bjn19670029.