二硫化碳对大鼠肝脏的影响。
Effects of carbon disulphide on the liver of rats.
作者信息
Bond E J, Butler W H, De Matteis F, Barnes J M
出版信息
Br J Ind Med. 1969 Oct;26(4):335-7. doi: 10.1136/oem.26.4.335.
Abstract
335-337. Normal rats surviving a single oral dose of carbon disulphide (CS) show liver enlargement and depression of drug-metabolizing enzymes but no liver necrosis. If the drug-metabolizing enzymes are stimulated by phenobarbitone before exposure to CS the LD does not change but liver necrosis is produced.
摘要
335 - 337。单次口服二硫化碳（CS）后存活的正常大鼠出现肝脏肿大和药物代谢酶活性降低，但无肝坏死。如果在接触CS之前用苯巴比妥刺激药物代谢酶，半数致死量（LD）不变，但会产生肝坏死。
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