Uchida Y, Nakamura F, Hirose J, Oshima T, Morita T, Morizuki S, Sasaki T, Tsubouchi N
Second Department of Internal Medicine, University of Tokyo, Japan.
Am Heart J. 1996 Jan;131(1):107-14. doi: 10.1016/s0002-8703(96)90058-7.
To examine feasibility of percutaneous cardioscopy for diagnosis of idiopathic myocarditis, cardioscopic appearance of the left ventricle and biopsy findings were compared in 21 such patients. The endocardial surface was milky white, red, pink, or reddish brown and edematous at the segments that exhibited histologic changes of acute myocarditis; purplish red in those that exhibited chronic active myocarditis; and yellow in those that exhibited chronic inactive or healed myocarditis. Follow-up study by repeated cardioscopy and biopsy in six patients revealed that the milky white surface disappeared and that the red, pink, and reddish brown surfaces changed to purplish red and then to yellow or white. The results indicate that the endocardial coloration of the left ventricle represents histologic changes and that cardioscopy is feasible for macroscopic pathologic diagnosis and for follow-up of idiopathic myocarditis.
为了研究经皮心脏镜检查诊断特发性心肌炎的可行性，对21例此类患者的左心室心脏镜表现和活检结果进行了比较。在表现为急性心肌炎组织学改变的节段，心内膜表面呈乳白色、红色、粉红色或红棕色且水肿；在表现为慢性活动性心肌炎的节段呈紫红色；在表现为慢性非活动性或愈合性心肌炎的节段呈黄色。对6例患者进行重复心脏镜检查和活检的随访研究发现，乳白色表面消失，红色、粉红色和红棕色表面变为紫红色，然后变为黄色或白色。结果表明，左心室心内膜颜色变化代表组织学改变，心脏镜检查对于特发性心肌炎的宏观病理诊断和随访是可行的。
