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[左心室动脉瘤的外科治疗。近期和远期结果。基于121例连续病例分析]

[Surgical treatment of aneurysms of the left ventricle. Immediate and long-term results. Apropos of a consecutive series of 121 cases].

作者信息

Valla J, Leguerrier A, Corbineau H, Sevray B, Langanay T, Le Couls H, Sellin M, Rioux C, Logeais Y

机构信息

Clinique Chirurgicale Cardiovasculaire et Thoracique, CHU, Rennes.

出版信息

Ann Chir. 1995;49(9):816-23.

PMID:8554279
Abstract

From 1978 to 1992, 121 cases of postinfarction left ventricular aneurysm (99 males, 22 females, mean age 60 years) were operated on. The authors insist on a high rate of clinical arhythmogenicity (31.4%) and associated mechanical complications (21%). 76% of patients were in functional NYHA class III or IV. Resection was performed in 90% of patients, plication in 10%. 58% underwent coronary artery bypass grafting (1.7 graft/patient), 16% encircling ventriculotomy, 8% mitral valve replacement and 13% closure of ventricular septal defect. Operative mortality was 14.9% (10% when other mechanical complications where excluded). 5-year survival is 67.9%. Late cardiac deaths are as follow: left ventricular failure (1.8% A/P), Sudden death (1.4% A/P), Myocardial infarction (0.6% A/P). 82% of survivals are in functional NYHA class I or II. Only functional class NYHA III or IV is predictive of late death. We conclude that postinfarction left ventricular aneurysm remains a high risk complication especially when associated with other mechanical complications. When arhythmogenicity is present we suggest rhythmologic surgery and in all cases, complete revascularization.

摘要

1978年至1992年期间,对121例心肌梗死后左心室室壁瘤患者(男性99例,女性22例,平均年龄60岁)进行了手术。作者强调临床心律失常发生率较高(31.4%)以及相关机械并发症发生率较高(21%)。76%的患者心功能为纽约心脏协会(NYHA)Ⅲ级或Ⅳ级。90%的患者进行了切除术,10%进行了折叠术。58%的患者接受了冠状动脉旁路移植术(平均每位患者移植1.7支血管),16%进行了心室内膜环缩术,8%进行了二尖瓣置换术,13%进行了室间隔缺损修补术。手术死亡率为14.9%(排除其他机械并发症时为10%)。5年生存率为67.9%。晚期心脏死亡情况如下:左心衰竭(每年1.8%)、猝死(每年1.4%)、心肌梗死(每年0.6%)。82%的存活患者心功能为NYHAⅠ级或Ⅱ级。只有NYHAⅢ级或Ⅳ级的心功能是晚期死亡的预测因素。我们得出结论,心肌梗死后左心室室壁瘤仍然是一种高风险并发症,尤其是与其他机械并发症相关时。当存在心律失常时,我们建议进行节律性手术,并且在所有情况下都要进行完全血运重建。

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