Zielinsky P, Firpo C M, de Lima R P, Martha V F, Silva E S
Instituto de Cardiologia do Rio Grande do Sul/Fundação Universitária de Cardiologia, Porto Alegre, RS.
Arq Bras Cardiol. 1995 Aug;65(2):153-7.
To test the hypothesis that the redundancy of the septum primum is more pronounced in fetuses with atrial premature beats than in normal fetuses.
Twenty-five consecutive fetuses with atrial premature beats detected by prenatal echocardiography as the sole alteration at a mean gestational age of 34 +/- 3.3 (26 to 38) weeks and a mean maternal age of 27 +/- 6.5 (18 to 39) years made up the study group. The control group was formed by 50 consecutive fetuses without rhythm disturbances and normal prenatal echocardiography, examined at a mean gestational age of 33.9 +/- 3 (26 to 39) weeks and a mean maternal age of 31 +/- 5.8 (18 to 43) years. A redundancy index (RI) was obtained as a ratio between the maximal septum primum excursion and the maximal left atrium diameter during atrial diastole, at the 4-chamber projection. Statistical analysis utilized the unpaired Student-Fisher's "t" test.
The RI in the study group varied from 0.50 to 1.00 (mean = 0.758 +/- 0.127) and in the control group in ranged from 0.29 to 0.67 (mean = 0.449 +/- 0.080). These differences were statistically significant for p < 0.0001.
Septum primum is more redundant in fetuses with atrial premature beats than in those with normal regular rhythm. Although it is still speculative that this feature may have a cause-effect relationship, the measurement of the RI during routine fetal echocardiography may allow detection of a potential risk factor FOR developing atrial arrhythmias.
验证如下假设，即与正常胎儿相比，房性早搏胎儿的原发隔冗余更为明显。
研究组由25例连续的胎儿组成，这些胎儿通过产前超声心动图检测出房性早搏，且这是唯一的异常情况，平均胎龄为34±3.3（26至38）周，母亲平均年龄为27±6.5（18至39）岁。对照组由50例连续的胎儿组成，这些胎儿无节律紊乱且产前超声心动图正常，平均胎龄为33.9±3（26至39）周，母亲平均年龄为31±5.8（18至43）岁。在四腔心切面，通过舒张期最大原发隔偏移与最大左心房直径之比获得冗余指数（RI）。统计分析采用非配对学生 - 费舍尔“t”检验。
研究组的RI在0.50至1.00之间（平均 = 0.758±0.127），对照组的RI在0.29至0.67之间（平均 = 0.449±0.080）。这些差异具有统计学意义，p < 0.0001。
与节律正常的胎儿相比，房性早搏胎儿的原发隔冗余更为明显。尽管目前仍推测这一特征可能存在因果关系，但在常规胎儿超声心动图检查中测量RI可能有助于检测发生房性心律失常的潜在危险因素。
