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怀孕早期暴露于磁场中的小鼠发生胎儿丢失。

Fetal loss in mice exposed to magnetic fields during early pregnancy.

作者信息

Svedenstål B M, Johanson K J

机构信息

Department of Radioecology, Swedish University of Agricultural Sciences, Uppsala, Sweden.

出版信息

Bioelectromagnetics. 1995;16(5):284-9. doi: 10.1002/bem.2250160503.

Abstract

The effects of low-frequency magnetic fields (MFs) on early pregnancy were studied in CBA/S mice. The magnetic field was a 20 kHz, 15 microT sawtooth. Pregnant females were divided into four groups, two control groups and two exposed groups. One group was exposed to MFs continuously from day 1 postconception (pc) until day 5.5 pc, and the other group was exposed continuously until day 7 pc. All animals were sacrificed on day 19 pc, the day before partus, and their uterine contents were analyzed. No significant increase in the resorption (early fetal death) rate was found in the exposed animals compared to the sham controls. In the group exposed during days 1.0-5.5 pc, the body weight and length of the living fetuses were significantly decreased. Except on day 3 pc (progesterone) and day 13 pc (calcium) in the treated groups, there were no significant differences in progesterone and calcium levels in peripheral blood. Implantation occurred on the same day in MF-treated and control animals.

摘要

在CBA/S小鼠中研究了低频磁场(MFs)对早期妊娠的影响。磁场为20kHz、15微特斯拉的锯齿波。怀孕雌性小鼠被分为四组,两个对照组和两个暴露组。一组从受孕后第1天(pc)持续暴露于MFs直至第5.5天pc,另一组持续暴露直至第7天pc。所有动物在妊娠第19天(分娩前一天)处死,并分析其子宫内容物。与假对照组相比,暴露动物的吸收(早期胎儿死亡)率没有显著增加。在第1.0 - 5.5天pc期间暴露的组中,存活胎儿的体重和长度显著降低。除了在治疗组的第3天pc(孕酮)和第13天pc(钙),外周血中孕酮和钙水平没有显著差异。MF处理组和对照组的着床在同一天发生。

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