Sergeeva T I, Iastrebov V V
Zh Mikrobiol Epidemiol Immunobiol. 1977 Mar(3):98-101.
For the first time in the USSR, as a result of all-around analysis of the problems connected with tetanus prophylaxis under conditions of the Arkhangelsk region the authors conducted a trial on the suspension of the use of antitetanus serum in trauma. Besides the elimination of the population allergization, replacement of the antitetanus serum with the toxioid facilitated the emergency prophylaxis of tetanus, created prerequisites for the immunity maintenance at the protective level in the population, and served as the necessary stage along the route of further improvement of emergency prophylaxis and elimination of tetanus.
在苏联,作者们首次在阿尔汉格尔斯克地区的条件下,对与破伤风预防相关的问题进行了全面分析,从而开展了一项关于在创伤中暂停使用抗破伤风血清的试验。除了消除人群过敏反应外,用类毒素替代抗破伤风血清有助于破伤风的紧急预防,为维持人群保护性水平的免疫力创造了前提条件,并且是进一步改进紧急预防和消除破伤风道路上的必要阶段。