Puri B K, Lekh S K, Langa A, Zaman R, Singh I
Department of Psychiatry, Charing Cross Hospital, London, England.
J Intellect Disabil Res. 1995 Oct;39 ( Pt 5):442-6. doi: 10.1111/j.1365-2788.1995.tb00549.x.
The mortality experiences of a hospitalized mentally handicapped population between 1981 and 1990 (inclusive) were examined. A continued trend for increasing longevity in both males and females was found, with mean ages at death now approaching those in the general population. The commonest cause of death was non-tubercular respiratory infection, from which patients were particularly at risk during the months of December to February (inclusive). Patients diagnosed as suffering from psychoses other than schizophrenia and mood disorder had an increased mortality and should be thoroughly investigated for the presence of organic pathology. Epilepsy and Down's syndrome were associated with increased risk of earlier death, although in the case of Down's syndrome there has been a marked increase in longevity.
对1981年至1990年(含)期间住院的智力障碍人群的死亡情况进行了调查。发现男性和女性的寿命均呈持续增长趋势,目前的平均死亡年龄已接近普通人群。最常见的死亡原因是非结核性呼吸道感染,患者在12月至2月(含)期间尤其容易感染。被诊断患有除精神分裂症和情绪障碍以外的精神病的患者死亡率较高,应彻底检查是否存在器质性病变。癫痫和唐氏综合征与过早死亡风险增加有关,不过就唐氏综合征而言,其寿命已显著延长。