Edelman D A, Grant S, van Os W A
Medical Research Consultants, San Diego, California, USA.
Int J Fertil Menopausal Stud. 1995 Sep-Oct;40(5):274-80.
Since their introduction in 1962, silicone gel-filled breast implants have been used by an estimated one to two million women. Questions concerning an increased cancer risk to these women have been raised. A review of the medical literature, including case reports, case series, physician surveys, case-control studies, and cohort studies, failed to turn up any evidence which associated the use of silicone breast implants with either an increased risk of breast cancer or an increased risk of a more advanced stage of cancer at the time of cancer diagnosis. The available data do not indicate any significant difference between the characteristics of the breast cancers of women with breast implants and those of women in control populations.
自1962年首次引入以来，估计已有100万至200万女性使用了硅胶填充乳房植入物。关于这些女性患癌风险增加的问题已经出现。对医学文献的回顾，包括病例报告、病例系列、医生调查、病例对照研究和队列研究，均未发现任何证据表明使用硅胶乳房植入物会增加患乳腺癌的风险，或在癌症诊断时增加癌症处于更晚期阶段的风险。现有数据并未表明植入乳房植入物的女性与对照人群中女性的乳腺癌特征存在任何显著差异。
