Kjøller K H, Krag C, Friis S
Plastikkirurgisk afdeling V, Amtssygehuset i Herlev.
Ugeskr Laeger. 1997 Mar 17;159(12):1744-8.
Sarcomas have been shown to develop next to foreign body implants, silicone included, in animal experiments. However, this carcinogenesis is not believed to have any human relevance. A review of the existing epidemiological studies suggests that women with silicone breast implants have a reduced risk for developing breast cancer. However, the presence of breast implants does obscure mammographic visualization as well as palpation of mammary tissue. This has led to the assumption that breast cancer detection could be compromised in women with breast implants. In the few studies that have dealt with this issue, women with breast implants were diagnosed with the same stage of disease as women without implants. However, the percentage of false negative mammographies was increased in one study. In conclusion, there is currently no evidence of an association between breast implants and cancer or postponed breast cancer detection.
在动物实验中，已证实肉瘤会在包括硅胶在内的异物植入物旁发生。然而，这种致癌作用被认为与人类无关。对现有流行病学研究的综述表明，植入硅胶乳房假体的女性患乳腺癌的风险降低。然而，乳房假体的存在确实会影响乳房X光检查的成像以及乳腺组织的触诊。这导致人们认为乳房假体女性的乳腺癌检测可能会受到影响。在少数涉及此问题的研究中，植入乳房假体的女性与未植入假体的女性被诊断出处于相同的疾病阶段。然而，在一项研究中，乳房X光检查假阴性的比例有所增加。总之，目前没有证据表明乳房假体与癌症之间存在关联，也没有证据表明会延迟乳腺癌的检测。
