Bons N, Szafarczyk A, Assenmacher I
Acta Anat (Basel). 1977;97(3):333-8.
Female albino rats were exposed during 3 weeks to various photoperiodic sequences and levels of illumination. As long as the light span of the photoperiod did not exceed 12L-12D, the damaging effects of the light, even when intese (3,000 lx), on the retinal were relatively limited. On the other hand, the 14L-10D photoperiodic regimen that is usually used in standard rat animaleries produced marked degenerative lesions on the photoreceptors under either 1,200 or 3,000 1x. Under lighting schedules of 21L-15D or 28L-20D, the photoreceptors were heavily injured by 1,200 OR 3,000 1X. The degenerative process affected all the photoreceptive cells as well as their various components: rods, cones, nucleus and synaptic endings.
将雌性白化大鼠暴露于不同的光周期序列和光照水平下3周。只要光周期的光照时长不超过12小时光照-12小时黑暗,即使光照强度很高(3000勒克斯),光对视网膜的损伤作用也相对有限。另一方面,标准大鼠饲养室通常采用的14小时光照-10小时黑暗的光周期方案,在1200勒克斯或3000勒克斯的光照强度下,都会在光感受器上产生明显的退行性病变。在21小时光照-15小时黑暗或28小时光照-20小时黑暗的光照时间表下,1200勒克斯或3000勒克斯的光照会使光感受器严重受损。退行性病变过程影响了所有光感受细胞及其各个组成部分:视杆细胞、视锥细胞、细胞核和突触末梢。