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[关于用溴氰菊酯药浴家犬以阻断内脏利什曼病传播的研究]

[Studies on the deltamethrin-medicated bath of domestic dogs for interrupting visceral leishmaniasis transmission].

作者信息

Xiong G, Jin C, Hong Y, Su Z, Xue P, Xie W, Zhang A, Li G, Gao B

机构信息

Institute of Parasitic Diseases, Chinese Academy of Preventive Medicine, Shanghai.

出版信息

Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi. 1995;13(3):178-81.

PMID:8556791
Abstract

In a previous paper, it was reported that deltamethrin-medicated bath of domestic dogs had a strong killing effect against Ph. chinensis, and could also inhibit its blood sucking ability or cause its death shortly after blood sucking. The effect could last for 30 days to 114 days, and mostly for 2 months in the local area. Based on our previous study, three villages (Yongle, Yongfeng, Anle) and a town (Chengguan) were selected from the mountainous region with high incidence of visceral leishmaniasis in Nanping County, northern Sichuan for carrying out an extensive experiment of medicated bathing of domestic dogs, where there were 13 new infected cases in the year of 1991 before the experiment. During the sandfly season in 1992, two rounds of medicated bathing of dogs were conducted, the drug concentration used was 50 ppm. From September 1992 to August 1993, the number of new infected cases was 11 in the above mentioned three villages and a town. Another two rounds of medicated bathing of dogs had been conducted during the sandfly season in 1993. The results show that there was no new infection from September 1993 to October 1994 in the three villages and a town, indicating that through two years' consecutive extensive medicated bathing of dogs in the endemic areas, canine visceral leishmaniasis transmission had been significantly interrupted. The authors consider that in the mountainous region of southern Gansu and northern Sichuan where it has been difficult to treat dogs, it might be more practical to use deltamethrin bathing of dogs for interrupting the transmission of canine visceral leishmaniasis.

摘要

在之前的一篇论文中报道,给家犬进行溴氰菊酯药浴对中华白蛉有很强的杀灭作用,还能抑制其吸血能力或使其吸血后不久死亡。这种效果可持续30天至114天,在当地大多可持续2个月。基于我们之前的研究,从四川北部南坪县内脏利什曼病高发山区选取了三个村(永乐、永丰、安乐)和一个镇(城关),对家犬进行广泛的药浴实验,实验前的1991年该地有13例新感染病例。1992年白蛉季节,对犬进行了两轮药浴,所用药物浓度为50 ppm。1992年9月至1993年8月,上述三个村和一个镇的新感染病例数为11例。1993年白蛉季节又对犬进行了两轮药浴。结果显示,1993年9月至1994年10月,这三个村和一个镇没有新的感染病例,表明通过在疫区连续两年对犬进行广泛的药浴,犬内脏利什曼病的传播已被显著阻断。作者认为,在甘肃南部和四川北部难以对犬进行治疗的山区,用溴氰菊酯给犬药浴来阻断犬内脏利什曼病的传播可能更具实际意义。

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