Stine S M, Krystal J H, Kosten T R, Charney D S
Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06520, USA.
Drug Alcohol Depend. 1995 Oct;39(3):245-52. doi: 10.1016/0376-8716(95)01174-4.
This double-blind placebo-controlled treatment study tested the efficacy of mazindol in currently cocaine-dependent out-patients. Forty-three patients were randomized to mazindol (2 mg QD) vs. placebo treatment for 6 weeks. All patients received weekly group counseling. Patients improved with respect to objective (urine toxicology) and subjective (self-report of times used, dollars spent, craving, etc.) measures. There was no response difference between patients treated with mazindol and those who received placebo.
