体重减轻对血浆和尿液尿酸及血脂水平的影响。

The effect of weight loss on plasma and urinary uric acid and lipid levels.

作者信息

Scott J T, Sturge R A

出版信息

Adv Exp Med Biol. 1977;76B:274-7. doi: 10.1007/978-1-4684-3285-5_41.

Abstract

Plasma uric acid levels in 35 obese gouty and non-gouty subjects showed a highly significant mean fall of 0.6 mg/100 ml after weight reduction on a low-calorie diet. Urinary urate also fell by a mean value of 87 mg/100 ml. Serum cholesterol and triglyceride levels have been studied in 20 of the subjects. Both have shown some overall fall with weight loss. So far the degree of change of plasma urate has shown a correlation with that of cholesterol but not that of triglyceride, but further data are needed on these inter-relationships.

摘要

35名肥胖痛风患者和非痛风患者在低热量饮食减重后，血浆尿酸水平平均显著下降0.6mg/100ml。尿尿酸平均也下降了87mg/100ml。对其中20名受试者的血清胆固醇和甘油三酯水平进行了研究。两者均随体重减轻而出现一定程度的整体下降。到目前为止，血浆尿酸的变化程度与胆固醇的变化程度相关，但与甘油三酯的变化程度无关，但仍需要关于这些相互关系的更多数据。