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极低出生体重早产儿的婴儿神经行为表现与认知结果之间的关系。

Relations between infant neurobehavioral performance and cognitive outcome in very low birth weight preterm infants.

作者信息

Wallace I F, Rose S A, McCarton C M, Kurtzberg D, Vaughan H G

机构信息

Department of Otolaryngology, Rose F. Kennedy Center, Albert Einstein College of Medicine, Bronx, New York, 10461, USA.

出版信息

J Dev Behav Pediatr. 1995 Oct;16(5):309-17.

PMID:8557830
Abstract

The predictive utility of three aspects of neonatal neurobehavioral performance was examined in 144 very low birth weight (< 1500 g) preterms who were followed until 6 years of age. Visual-following and auditory-orienting composites derived from the Einstein Neonatal Neurobehavioral Assessment Scale were modestly related to the Mental Developmental Index (MDI) and IQ scores at several ages, whereas the active motility composite was only related to MDI scores at 1 year of age (corrected). Infants who showed deviant performance on both visual following and auditory orienting composites had significantly lower cognitive test scores at 1 and 6 years of age and were more likely to be classified as subaverage at 6 years of age (IQ < 85). Group differences were independent of both neonatal health status and motor scores and were not due to the performance of children with severe sensory impairments. These findings suggest that visual following and auditory orienting measured in the neonatal period can offer a useful way of indexing initial capacities.

摘要

对144名极低出生体重(<1500克)的早产儿进行了研究,考察了新生儿神经行为表现三个方面的预测效用,这些早产儿一直随访至6岁。源自爱因斯坦新生儿神经行为评估量表的视觉追踪和听觉定向综合指标在几个年龄段与心理发育指数(MDI)和智商得分有适度关联,而主动运动综合指标仅与1岁(校正后)的MDI得分相关。在视觉追踪和听觉定向综合指标上表现异常的婴儿在1岁和6岁时认知测试得分显著较低,且在6岁时更有可能被归类为低于平均水平(智商<85)。组间差异独立于新生儿健康状况和运动得分,且不是由严重感觉障碍儿童的表现所致。这些发现表明,新生儿期测量的视觉追踪和听觉定向可为索引初始能力提供一种有用的方法。

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