Størset P, Smith-Erichsen N, Vaagenes P
Department of Anaesthesia, Ullevål University Hospital, Oslo, Norway.
Intensive Care Med. 1995 Oct;21(10):797-801. doi: 10.1007/BF01700961.
To examine outcome in relation to organ function variables during early acute renal failure (ARF).
Retrospective inception cohort.
General intensive care unit (ICU).
69 consecutive ARF cases verified to have a creatinine clearance below 50 ml/min with no history of previous renal disease.
ICU survival.
Septic severity score (SSS), creatinine clearance, thrombocyte count, bilirubin concentration, cardiac inotropic support, PaO2/FIO2 ratio and oliguria were measured. No differences related to outcome were observed in patients surviving more than 7 days after ARF diagnosis. Patients dying within 7 days of ARF had a significantly higher (worse) SSS. Organ dysfunction was established at the time of ICU admission in the majority of cases.
The organ function variables tested in this study are of limited predictive value during the early stage of ARF.
研究急性肾衰竭（ARF）早期器官功能变量与预后的关系。
回顾性起始队列研究。
综合重症监护病房（ICU）。
69例连续的ARF病例，经证实肌酐清除率低于50 ml/min，且既往无肾脏疾病史。
ICU生存率。
测量脓毒症严重程度评分（SSS）、肌酐清除率、血小板计数、胆红素浓度、心脏正性肌力支持、动脉血氧分压/吸入氧分数值（PaO2/FIO2）比值及少尿情况。ARF诊断后存活超过7天的患者未观察到与预后相关的差异。在ARF发病7天内死亡的患者脓毒症严重程度评分显著更高（更差）。大多数病例在入住ICU时即已出现器官功能障碍。
本研究中所检测的器官功能变量在ARF早期阶段的预测价值有限。
