Wheeler D C, Feehally J, Walls J
Q J Med. 1986 Oct;61(234):977-84.
Acute renal failure carries a high mortality and little change in survival rate over the last three decades has been seen. Patients requiring intensive care, most of whom have developed acute renal failure following trauma or surgery, have a worse prognosis. The survival in this series of 100 consecutive patients admitted to one intensive care unit between 1976 and 1985 was 35 per cent. The only factors which differed significantly between the surviving and non-surviving patients were age, requirement for mechanical ventilation and maximum serum creatinine level before the first dialysis. It is difficult to predict outcome for an individual patient at the start of treatment and an aggressive approach to management is advocated.
急性肾衰竭死亡率高，过去三十年生存率几乎没有变化。需要重症监护的患者，其中大多数在创伤或手术后发生急性肾衰竭，预后较差。1976年至1985年间，在一家重症监护病房连续收治的100例患者中，生存率为35%。存活患者和非存活患者之间唯一有显著差异的因素是年龄、机械通气需求以及首次透析前的最高血清肌酐水平。在治疗开始时很难预测个体患者的预后，因此提倡积极的管理方法。
