Fetal blood sampling in the assessment of acute nonimmune hydrops fetalis.

Nonimmune hydrops fetalis can be associated with many fetal conditions. A fetal blood sample obtained from ultrasound-guided cordocentesis can offer vital information about the underlying cause of the nonimmune hydrops fetalis, and perinatal management can be planned accordingly. We attempted to evaluate a case of nonimmune hydrops fetalis conveying poor perinatal outcome through serial fetal blood sampling. Although we could establish no apparent reason for this acute case, fetal blood sampling in addition to ultrasonographic screening can play a key role in the management of the 'perplexing' nonimmune hydrops fetalis.