Katz S M, Bates O, Yudis M, Falkner B, Griffith E
Am J Clin Pathol. 1977 May;67(5):436-9. doi: 10.1093/ajcp/67.5.436.
The nephropathology associated with retroperitoneal fibrosis has been commonly related to compression of the ureters and hydronephrosis. This assumption has been made without the use of immunofluorescent microscopy and electron microscopy. The authors studied renal tissue from a patient with retroperitoneal fibrosis by light microscopy, immunofluorescent microscopy and electron microscopy. In addition to the gross and microscopic changes of obstructive nephropathy, histologic findings of glomerular immune-complex deposition were also present. It is postulated that in some cases of retroperitoneal fibrosis, destruction may be mediated by both obstructive and immunologic processes.
与腹膜后纤维化相关的肾病通常与输尿管受压及肾积水有关。这种假设是在未使用免疫荧光显微镜和电子显微镜的情况下做出的。作者通过光学显微镜、免疫荧光显微镜和电子显微镜对一名腹膜后纤维化患者的肾组织进行了研究。除了梗阻性肾病的大体和微观变化外，还存在肾小球免疫复合物沉积的组织学表现。据推测，在某些腹膜后纤维化病例中，破坏可能由梗阻性和免疫性过程共同介导。
