The' T G, Young M, Rosser S
Department of Pediatrics, District of Columbia General Hospital, Washington 20003, USA.
J Natl Med Assoc. 1995 Dec;87(12):889-91.
This article describes a case of spontaneous neonatal intestinal perforation in a preterm infant with evidence of intrauterine exposure to cocaine. Clinical, laboratory, radiological, surgical, and pathological finds were inconsistent with necrotizing enterocolitis. Three previous case reports had made the association between spontaneous focal neonatal intestinal perforation and prior intrauterine cocaine exposure; however, in each case, there were extenuating circumstances that may weaken the etiological link. The case described here appears to strengthen the association/etiological link. After all other causes of focal neonatal intestinal perforation have been excluded, the possibility of intrauterine exposure to cocaine should be considered.
本文描述了一例早产新生儿自发性肠穿孔病例，该患儿有宫内接触可卡因的证据。临床、实验室、放射学、手术及病理学检查结果均不符合坏死性小肠结肠炎。此前有三篇病例报告指出自发性局灶性新生儿肠穿孔与宫内可卡因暴露之间存在关联；然而，在每一个病例中，都存在一些情有可原的情况，可能会削弱这种病因联系。此处描述的病例似乎强化了这种关联/病因联系。在排除了新生儿局灶性肠穿孔的所有其他病因后，应考虑宫内接触可卡因的可能性。
