Andreasen V, Pugliese A
Department of Mathematics and Physics, Roskilde University, Denmark.
J Theor Biol. 1995 Nov 21;177(2):159-65.
A model of two competing infectious diseases with complete cross-protection sharing one host allows for coexistence, provided that the host population is subject to strong density regulation. The phenomenon is caused by the different ways in which host density affects transmission rate and transmission period. The analysis suggest that disease coexistence is most likely when the two diseases differ significantly in virulence and transmission and that the evolutionary stability of the two-disease association depends critically on details in the functional relationship between virulence and transmission.
一个具有完全交叉保护的两种竞争性传染病共享一个宿主的模型允许共存，前提是宿主种群受到强烈的密度调节。这种现象是由宿主密度影响传播率和传播期的不同方式引起的。分析表明，当两种疾病在毒力和传播方面有显著差异时，疾病共存的可能性最大，并且两种疾病关联的进化稳定性关键取决于毒力和传播之间功能关系的细节。
