Pitche P, Kombate K, Napo-Koura G, Mijiyawa M, Tchangai-Walla K
Service de Dermatologie, Centre Hospitalier Universitaire Tokoin, Lomé, Togo.
Med Trop (Mars). 1995;55(3):246-8.
The purpose of this retrospective study conducted in a dermatologic out patient clinic in Lomé was to assess the epidemiologic, clinical, and prognostic profile of Kaposi's sarcoma in Togo during the 15 years period between 1980 and 1994. Only patients who had undergone serologic tests for human immunodeficiency virus (HIV) were included. There were 30 patients (27 men and 3 women) with a mean age of 35.2 years (range: 17 to 59 years). Thirteen patients were seropositive (epidemic Kaposi's sarcoma or EPK) and 17 were seronegative (endemic Kaposi's sarcoma or ENK). The mean age of patients with EPK was lower than that of patients with ENK (30.0 vs 42.3 years). Extensive (92.3%) and edematous (90%) forms and involvement of the upper extremities (66.7%), trunk (01.6%), and mucosa (92.3%) were characteristic clinical features of EPK while localized nodular forms (92.3%) were characteristic of ENK. A death was noted after 5 years of follow-up in the ENK group as compared to 12 deaths after a mean follow-up of 15.95 years in the EPK group. This study illustrates the current profile of Kaposi's sarcoma in Black Africa where HIV infection has greatly changed clinical findings and prognosis.
这项在洛美一家皮肤科门诊进行的回顾性研究旨在评估1980年至1994年这15年间多哥卡波西肉瘤的流行病学、临床及预后情况。仅纳入了接受过人类免疫缺陷病毒（HIV）血清学检测的患者。共有30例患者（27名男性和3名女性），平均年龄35.2岁（范围：17至59岁）。13例患者血清学呈阳性（流行性卡波西肉瘤或EPK），17例血清学呈阴性（地方性卡波西肉瘤或ENK）。EPK患者的平均年龄低于ENK患者（30.0岁对42.3岁）。广泛型（92.3%）和水肿型（90%）以及上肢受累（66.7%）、躯干受累（61.6%）和黏膜受累（92.3%）是EPK的特征性临床特征，而局限性结节型（92.3%）是ENK的特征性表现。ENK组在随访5年后有1例死亡，而EPK组在平均随访15.95年后有12例死亡。这项研究阐明了在黑非洲地区卡波西肉瘤的当前情况，在该地区HIV感染极大地改变了临床表现和预后。
