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[鲍曼不动杆菌对突尼斯医院环境中使用的抗生素和消毒剂的敏感性]

[Sensitivity of Acinetobacter baumannii to antibiotics and disinfectants used in a Tunisian hospital milieu].

作者信息

Jennane S, Masmoudi A, Boudabous A, Fendri C

机构信息

Laboratoire de Bactériologie, l'Hôpital La Rabta et de la Faculté des Sciences, Tunis, Tunisie.

出版信息

Med Trop (Mars). 1995;55(3):255-7.

PMID:8559024
Abstract

Seventy-nine strains of Acinetobacter baumannii isolated from pathologic products obtained mainly from surgical and intensive care units at the Rabta Hospital in Tunisia were studied. The sensitivity of these bacteria to the antibiotics used singly or in combination was tested in order to determine the most effective agents. Sensitivity to the disinfectants routinely used in our hospital was also studied using the "dilution-neutralisation" method according to "AFNOR" norms in order to identify the product with the most powerful preventive effect for Acinetobacter baumannii infection. The bacteria tested were resistant to all antibiotics except imipernem, colistin, and some aminoglycosides. A combination of imipenem-amikacin was effective against all strains. Best disinfection was obtained after 5 minutes of bacterial contact with aldehyde, phenol and amphotere.

摘要

对从突尼斯拉卜塔医院外科和重症监护病房的病理产物中分离出的79株鲍曼不动杆菌进行了研究。测试了这些细菌对单独使用或联合使用的抗生素的敏感性,以确定最有效的药物。还根据“法国标准化协会”规范,采用“稀释中和”法研究了它们对我院常规使用的消毒剂的敏感性,以确定对鲍曼不动杆菌感染预防效果最强的产品。测试的细菌对除亚胺培南、多粘菌素和一些氨基糖苷类抗生素外的所有抗生素均耐药。亚胺培南-阿米卡星联合用药对所有菌株均有效。细菌与醛、苯酚和两性霉素接触5分钟后消毒效果最佳。

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