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西诺沙星、氨苄西林和氯霉素对志贺氏菌和非伤寒沙门氏菌的体外活性。

In vitro activity of cinoxacin, ampicillin, and chloramphenicol against Shigella and nontyphoid Salmonella.

作者信息

Rubinstein E, Shainberg B

出版信息

Antimicrob Agents Chemother. 1977 Apr;11(4):577-9. doi: 10.1128/AAC.11.4.577.

Abstract

The in vitro antibacterial activity of cinoxacin was compared with that of ampicillin and chloramphenicol against 26 strains of nontyphoid Salmonella and 44 strains of Shigella. Cinoxacin was found to have a lower minimal inhibitory concentration than ampicillin and chloramphenicol against all Salmonella and Shigella sonnei strains. Cinoxacin had minimal inhibitory concentrations similar to those of chloramphenicol but lower than those of ampicillin against Shigella flexneri and S. boydii strains.

摘要

将西诺沙星与氨苄西林和氯霉素对26株非伤寒沙门氏菌和44株志贺氏菌的体外抗菌活性进行了比较。结果发现,西诺沙星对所有沙门氏菌和宋内志贺氏菌菌株的最低抑菌浓度均低于氨苄西林和氯霉素。对于弗氏志贺氏菌和鲍氏志贺氏菌菌株,西诺沙星的最低抑菌浓度与氯霉素相似,但低于氨苄西林。

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