Moriyama H, Yanagi K, Ohtori N, Fukami M
Department of Otolaryngology, Jikei University School of Medicine, Tokyo, Japan.
Rhinology. 1995 Sep;33(3):166-70.
We discuss the results of endoscopic endonasal sinus surgery for chronic pan-sinusitis characterized by nasal polyposis, especially the effects of post-operative long-term administration of low-dose erythromycin (EM) therapy. The subjects analysed in this retrospective study are surgical cases who had initially been operated for chronic pan-sinusitis. They are classified into one group who has received a post-operative long-term, low-dose EM regimen and into another group who has not received this treatment. The groups have been compared with respect to: (1) the degree of improvement in the post-operative subjective symptoms; (2) postoperative objective findings of the ethmoidal sinus and the ostium of the frontal sinus; and (3) the degree of improvement in the maxillary sinus lesion. Better improvement is achieved in subjective symptoms and objective findings in the EM group than in the non-EM group.
我们讨论了以内镜下鼻内鼻窦手术治疗以鼻息肉为特征的慢性全鼻窦炎的结果，特别是术后长期给予低剂量红霉素（EM）治疗的效果。在这项回顾性研究中分析的对象是最初因慢性全鼻窦炎接受手术的病例。他们被分为一组接受术后长期低剂量EM治疗方案，另一组未接受该治疗。对两组进行了以下方面的比较：（1）术后主观症状的改善程度；（2）筛窦和额窦开口的术后客观检查结果；（3）上颌窦病变的改善程度。EM组在主观症状和客观检查结果方面比非EM组有更好的改善。
