紫罗精对聚肌苷酸-聚胞苷酸诱导干扰素的影响
Effects of ionenes on interferon induction by poly(inosinic acid) . poly(cytidylic acid).
作者信息
Clercq E D, Janik B, Sommer R G
出版信息
Antimicrob Agents Chemother. 1977 Apr;11(4):756-9. doi: 10.1128/AAC.11.4.756.
Abstract
Depending on the spacing of their positive charges, ionenes, a class of quaternary ammonium polymers, increased the interferon-inducing activity of poly(inosinic acid).poly(cytidylic acid) in mouse L-929 cells, whereas they did not enhance poly(inosinic acid).poly(cytidylic acid) induced interferon production in primary rabbit kidney and human skin fibrolast cells.
摘要
取决于其正电荷的间距，离子烯（一类季铵聚合物）可增强聚肌苷酸·聚胞苷酸在小鼠L-929细胞中的干扰素诱导活性，而在原代兔肾细胞和人皮肤成纤维细胞中，它们不会增强聚肌苷酸·聚胞苷酸诱导的干扰素产生。
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本文引用的文献
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Effect of DEAE-dextran on production of interferon induced by synthetic double-stranded RNA in L cell cultures.二乙氨基乙基葡聚糖对L细胞培养物中合成双链RNA诱导的干扰素产生的影响。
Proc Soc Exp Biol Med. 1968 Jul;128(3):708-10. doi: 10.3181/00379727-128-33105.
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Mechanisms of DEAE-dextran enhancement of polynucleotide induction of interferon.二乙氨基乙基葡聚糖增强多核苷酸诱导干扰素的机制。
Proc Soc Exp Biol Med. 1971 Apr;136(4):1111-4. doi: 10.3181/00379727-136-35440.
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The specificity of interferon induction in chick embryo cells by helical RNA.螺旋状RNA在鸡胚细胞中诱导干扰素的特异性。
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