Arboleda M, Castilho M C, Fonseca J C, Albuquerque B C, Saboia R C, Yoshida C F
Servicio Seccional de Salud de Antioquia, Instituto Colombiano de Medicina Tropical, Medellín, Colombia.
Trans R Soc Trop Med Hyg. 1995 Sep-Oct;89(5):481-3. doi: 10.1016/0035-9203(95)90074-8.
The State of Amazonas in the Brazilian Amazon region is an area of high prevalence of hepatitis B and D virus (HBV and HDV) infection. The aim of this study was to identify epidemiological patterns and risk factors of HBV and HDV infections in Barcelos, in the basin of the Negro river. A random sample (798 in all) of the total population in the urban area and in 2 rural villages was surveyed. A standardized questionnaire was used and blood samples were tested by enzyme-linked immunosorbent assay: 1.63% had hepatitis B surface antigen, 12.9% had anti-hepatitis B surface antibody and 21.4% had anti-hepatitis B core antigen. The overall prevalence of HBV infection was 24.6%. Anti-hepatitis D was present in 5 subjects, all of them non-natives, and hepatitis B e antigen in 2. A positive association between history of dental treatment with an unqualified dental surgeon was found (P < 0.05). These results suggest a low prevalence of HVB and HDV infection, in contrast with other parts of the Amazon area.
巴西亚马逊地区的阿马帕州是乙肝和丁型肝炎病毒（HBV和HDV）感染的高流行区。本研究旨在确定内格罗河流域巴塞卢斯地区HBV和HDV感染的流行病学模式及危险因素。对市区和2个乡村的总人口进行了随机抽样（共798人）调查。使用标准化问卷，并通过酶联免疫吸附测定法检测血样：1.63%的人有乙肝表面抗原，12.9%的人有乙肝表面抗体，21.4%的人有乙肝核心抗体。HBV感染的总体患病率为24.6%。5名受试者检测出抗丁型肝炎抗体，他们均为非本地人，2名受试者检测出乙肝e抗原。发现曾接受不合格牙医治疗与感染之间存在正相关（P<0.05）。这些结果表明，与亚马逊地区的其他地方相比，HVB和HDV感染的患病率较低。
