Fonseca J C, Simonetti S R, Schatzmayr H G, Castejón M J, Cesário A L, Simonetti J P
Hepatitis Laboratory, Institute of Tropical Medicine of Manaus, Amazonas, Brazil.
Trans R Soc Trop Med Hyg. 1988;82(3):469-71. doi: 10.1016/0035-9203(88)90166-6.
Serum samples were non-randomly obtained from apparently healthy inhabitants of 5 villages in the Amazonas State, Brazil. Sera were tested by enzyme immunoassay for the presence of hepatitis B surface antigen (HBsAg) and, if this was found, for antibody to hepatitis delta virus (HDV). Of 574 people tested, 96 (16.7%) were reactive for HBsAg and 33 of these (34.4%) for anti-HDV. The results were analysed according to sex, age and history of jaundice and showed a high prevalence of hepatitis B virus (HBV) and HDV infections in these asymptomatic persons, mainly in young people. The rates of prevalence observed in Amazonas for both HBV and HDV are perhaps among the highest in the world, demonstrating that these viruses are endemic in this region of Brazil.
血清样本是从巴西亚马孙州5个村庄的看似健康的居民中非随机获取的。通过酶免疫测定法检测血清中是否存在乙型肝炎表面抗原（HBsAg），如果检测到该抗原，则检测丁型肝炎病毒抗体（HDV）。在接受检测的574人中，96人（16.7%）HBsAg呈阳性，其中33人（34.4%）抗HDV呈阳性。根据性别、年龄和黄疸病史对结果进行分析，结果显示这些无症状人群中乙型肝炎病毒（HBV）和HDV感染的患病率很高，主要集中在年轻人中。在亚马孙州观察到的HBV和HDV患病率可能是世界上最高的之一，这表明这些病毒在巴西的这一地区呈地方性流行。
