Nash P A, Bihrle R, Gleason P E, Adams M C, Hanke C W
Department of Urology, Indiana University Medical Center, Indianapolis 46202-5265, USA.
Urology. 1996 Jan;47(1):108-10. doi: 10.1016/s0090-4295(99)80392-6.
To report the use of conservative extirpative surgical techniques to manage glanular carcinoma in situ with significant urethral extension.
Over a 5-year period, 2 patients with carcinoma in situ of the glans with significant distal urethral involvement, who refused penectomy, were managed with combined treatment modalities using Mohs' micrographic surgery and distal urethrectomy with immediate urethral reconstruction.
At follow-up of 5 years and of 12 months, there has been no evidence of meatal or proximal urethral recurrence.
Mohs' micrographic surgical excision and distal urethrectomy with immediate urethral reconstruction offers an acceptable alternative to partial penectomy in patients with perimeatal carcinoma in situ who fail conservative treatment or refuse penectomy.
报告采用保守性切除手术技术治疗伴有显著尿道扩展的原位阴茎头癌。
在5年期间，2例阴茎头原位癌且远端尿道有显著受累、拒绝阴茎切除术的患者，采用Mohs显微外科手术和远端尿道切除术并立即进行尿道重建的联合治疗方式进行处理。
在5年和12个月的随访中，没有尿道口或近端尿道复发的证据。
对于保守治疗失败或拒绝阴茎切除术的尿道口原位癌患者，Mohs显微外科手术切除和远端尿道切除术并立即进行尿道重建是部分阴茎切除术的一种可接受的替代方法。
