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一种用于控制禽球虫病的减毒活疫苗:在英国肉种鸡和后备蛋鸡群中的试验

A live attenuated vaccine for the control of avian coccidiosis: trials in broiler breeders and replacement layer flocks in the United Kingdom.

作者信息

Shirley M W, Bushell A C, Bushell J E, McDonald V, Roberts B

机构信息

Institute for Animal Health, Compton Laboratory, Newbury.

出版信息

Vet Rec. 1995 Oct 28;137(18):453-7. doi: 10.1136/vr.137.18.453.

DOI:10.1136/vr.137.18.453
PMID:8560713
Abstract

Losses caused by coccidiosis are a significant problem in the rearing of breeder and layer flocks. A live vaccine has been developed that contains attenuated lines of the seven species of Eimeria that infect the chicken. The attenuated lines were derived from virulent strains by selection for earlier development in chickens. In 11 field trials, the performance of vaccinated chicks was compared with that of matched controls receiving conventional drug prophylaxis. The vaccine was given in the drinking water to 116,600 young chickens and provided excellent control of coccidiosis. The occurrence of coccidial oocysts in the litter, coccidial lesions post mortem and overt coccidiosis was markedly lower in the vaccinated birds than in the controls.

摘要

球虫病造成的损失是种鸡和蛋鸡养殖中的一个重大问题。现已研发出一种活疫苗,其包含感染鸡的七种艾美耳球虫的减毒株系。这些减毒株系是通过选择在鸡体内发育较早的毒株从强毒株中衍生而来的。在11项田间试验中,将接种疫苗的雏鸡的性能与接受常规药物预防的配对对照组进行了比较。该疫苗通过饮水给予116,600只幼鸡,并对球虫病提供了出色的防控效果。接种疫苗的鸡群中垫料里球虫卵囊的出现、死后球虫病变以及明显的球虫病情况均显著低于对照组。

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