Baker R R
Ann Surg. 1977 May;185(5):543-7. doi: 10.1097/00000658-197705000-00006.
Because an increasing number of women do not wish to be anesthetized not knowing the specific diagnosis and not knowing if they will awaken with or without their breast, the traditional approach of biopsy under general anesthesia, frozen section and simultaneous mastectomy has been abandoned in most instances. One-hundred and fifty-three consecutive biopsies have been performed under local anesthesia. Nineteen patients proved to have a carcinoma, 23 patients had non-obligate precursors of carcinoma, five patients had a lymphoma and the remaining patients had benign disease. No significant complications occurred. Breast biopsies under local anesthesia avoid a good deal of psychologic trauma to the patient and allow the surgeon to plan therapy based on a precise histologic diagnosis. There are also substantial savings on both the direct and indirect cost of a breast biopsy under local anesthesia compared to a similar procedure under general anesthesia.
由于越来越多的女性不愿在不了解具体诊断结果且不知道术后是否会保留乳房的情况下接受麻醉，因此在大多数情况下，传统的全身麻醉下活检、冰冻切片检查并同时进行乳房切除术的方法已被摒弃。我们连续对153例患者进行了局部麻醉下的活检。其中19例患者被证实患有癌症，23例患者有癌前病变，5例患者患有淋巴瘤，其余患者为良性疾病。未发生严重并发症。局部麻醉下的乳房活检避免了给患者带来大量心理创伤，并且能让外科医生根据精确的组织学诊断来制定治疗方案。与全身麻醉下的类似手术相比，局部麻醉下乳房活检的直接和间接成本也大幅降低。
