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成人幕上蛛网膜囊肿。从病理生理和手术角度对两例病例的讨论。

Supratentorial arachnoid cysts in adults. A discussion of two cases from a pathophysiologic and surgical perspective.

作者信息

Dyck P, Gruskin P

出版信息

Arch Neurol. 1977 May;34(5):276-9. doi: 10.1001/archneur.1977.00500170030004.

Abstract

Large congenital arachnoid cysts are a rare cause of increased intracranial pressure and progressive neurologic deficits in adult life. We describe two patients, diagnosed by computerized axial tomography and surgically treated. The pertinent medical literature was reviewed. The outer cyst membranes were excised, and a communication between cyst and subarachnoid space was established. When possible, the membranes and fluid content of these lesions should be studied. This fluid is best obtained by aspiration prior to dural incision. At present, three etiologic mechanisms of cyst enlargement appear tenable: (1) secretion of fluid by ependymal cells, (2) fluid ingress due to an osmotic gradient, and finally, (3) trapping of fluid by a ball-valve mechanism. Regardless of the reasons why these lesions enlarge, drainage of cyst content into the venous system warrants a clinical consideration.

摘要

大型先天性蛛网膜囊肿是成人颅内压升高和进行性神经功能缺损的罕见原因。我们描述了两名经计算机断层扫描诊断并接受手术治疗的患者。对相关医学文献进行了回顾。切除囊肿外膜,并建立囊肿与蛛网膜下腔之间的交通。如果可能,应研究这些病变的膜和液体成分。这种液体最好在切开硬脑膜之前通过抽吸获得。目前,囊肿扩大的三种病因机制似乎合理:(1)室管膜细胞分泌液体,(2)由于渗透梯度导致液体进入,最后,(3)通过球阀机制截留液体。无论这些病变扩大的原因是什么,将囊肿内容物引流到静脉系统值得临床考虑。

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