Caroli S, Coni E, Violante N, Petrucci F, Caimi S
Laboratorio di Tossicologia Applicata, Istituto Superiore di Sanità, Roma.
Ann Ist Super Sanita. 1995;31(2):219-24.
The various steps of the analytical process are taken into account with particular reference to problems arising in sampling biological materials, their storage, pretreatment, digestion (when necessary) and determination. Emphasis is laid on the fact that the availability of analytical equipment with exceptional detection power is not always flanked by an equivalent ability to control phenomena of contamination and/or loss of analytes as well as to check and guarantee the accuracy of experimental data. In this context, proper use of the most popular analytical techniques for the determination of trace elements and the adoption of strict procedural conditions for data reliability are briefly discussed.
分析过程的各个步骤都被考虑在内,尤其涉及到生物材料采样、储存、预处理、(必要时)消解以及测定过程中出现的问题。需要强调的是,具备卓越检测能力的分析设备,其控制分析物污染和/或损失现象以及检查和保证实验数据准确性的能力,并不总是与之相当。在此背景下,简要讨论了最常用的微量元素测定分析技术的正确使用以及为保证数据可靠性而采用的严格程序条件。