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[颞骨朗格汉斯细胞组织细胞增多症]

[Langerhans cell histiocytosis of the temporal bone].

作者信息

Issing P R, Ernst A, Kempf H G, Buhr T, Lenarz T

机构信息

Klinik für HNO Heilkunde, Medizinische Hochschule Hannover.

出版信息

Laryngorhinootologie. 1995 Nov;74(11):702-6. doi: 10.1055/s-2007-997829.

Abstract

BACKGROUND

The localized form of the Langerhans cell histiocytosis was referred to earlier as eosinophilic granuloma, which has the best prognosis of all histiocytosis syndromes concerning survival. The non-malignant proliferative disorder of the histiocytic system is still of unknown etiology. Characteristic radiographic signs are osteolytic lesions.

PATIENT

We report on an otologic manifestation of a 20-year-old man's temporal bone, which developed three years after a successful treatment of an eosinophilic granuloma of the mandible.

RESULTS

Surgery and low-dose irradiation led to a complete remission of the disease. Other manifestations of the disease were not detected until now.

CONCLUSIONS

In the presence of chronic aural discharge, Langerhans cell histiocytosis must bei considered in differential diagnosis and a histopathological examination should be performed.

摘要

背景

朗格汉斯细胞组织细胞增多症的局限性形式曾被称为嗜酸性肉芽肿,在所有组织细胞增多症综合征中,就生存率而言其预后最佳。组织细胞系统的非恶性增殖性疾病病因仍不明。特征性影像学表现为溶骨性病变。

患者

我们报告一名20岁男性颞骨的耳科表现,该表现出现在下颌骨嗜酸性肉芽肿成功治疗三年后。

结果

手术和低剂量放疗使疾病完全缓解。目前未检测到该疾病的其他表现。

结论

在存在慢性耳漏的情况下,鉴别诊断时必须考虑朗格汉斯细胞组织细胞增多症,应进行组织病理学检查。

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