Tariot P N, Schneider L S, Katz I R
Department of Psychiatry, University of Rochester School of Medicine and Dentistry, New York, USA.
J Geriatr Psychiatry Neurol. 1995 Oct;8 Suppl 1:S28-39. doi: 10.1177/089198879500800105.
Studies have shown that the vast majority of patients with dementia experience some psychopathologic symptoms during the course of their illness. Symptoms of this nature, which can include frightening hallucinations or anxiety of phobic proportions, are subjectively distressing and can lead both to unsafe or violent situations as well as to the preventable use of inappropriate medication, physical restraint, and frequently to institutionalization. These psychopathologic manifestations of dementia often prove to be a burden on family, caregivers, and the health care system as well. This article presents an overview of the assessment and management of agitation as it relates to the severity of dementia symptoms and cognitive deterioration. Specifically, the use of anticonvulsant and other non-neuroleptic therapies is examined.
研究表明，绝大多数痴呆患者在病程中会出现一些精神病理症状。这类症状包括令人恐惧的幻觉或达到恐惧症程度的焦虑，会给患者带来主观痛苦，既可能导致不安全或暴力情况，也可能导致不当用药、身体约束等可预防的情况，还常常导致患者被送进养老院。痴呆的这些精神病理表现往往也给家庭、护理人员和医疗保健系统带来负担。本文概述了与痴呆症状严重程度和认知衰退相关的激越的评估与管理。具体而言，探讨了抗惊厥药物及其他非抗精神病药物疗法的使用。
