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[人参根及茎叶皂苷对大鼠学习、记忆及脑内生物源性单胺的影响]

[Effects of Chinese ginseng root and stem-leaf saponins on learning, memory and biogenic monoamines of brain in rats].

作者信息

Wang A, Cao Y, Wang Y, Zhao R, Liu C

机构信息

Shenyang Pharmaceutical University.

出版信息

Zhongguo Zhong Yao Za Zhi. 1995 Aug;20(8):493-5, inside backcover.

PMID:8561889
Abstract

The present investigation has shown that Ginseng root saponins (ig, 50mg/kg x 7d) facilitate the learning and memory of normal male Wistar rats, while the effect of Ginseng stem-leaf saponins (ig, 50mg/kg x 7d) on antielectrconvulsive shock-induced impairment of memory consolidation in rats is more intensive than that of root saponins. Both Ginseng root and stem-leaf saponins can significantly raise the levels of biogenic monoamines in normal rat's brain.

摘要

目前的研究表明,人参根皂苷(灌胃,50mg/kg×7天)可促进正常雄性Wistar大鼠的学习和记忆,而人参茎叶皂苷(灌胃,50mg/kg×7天)对大鼠抗电惊厥休克诱导的记忆巩固损伤的作用比根皂苷更强。人参根皂苷和茎叶皂苷均可显著提高正常大鼠脑内生物源性单胺的水平。

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