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一名乳腺癌患者出现获得性凝血因子VIII抑制剂,伴有模拟深静脉血栓形成的肌肉血肿。

Presentation of an acquired factor VIII inhibitor with a muscular haematoma mimicking a deep venous thrombosis in a patient with breast cancer.

作者信息

López R, Mateo J, Cruz J, López A, Urrutia T, Fontcuberta J

机构信息

Haematology Department, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.

出版信息

Blood Coagul Fibrinolysis. 1995 Oct;6(7):680-2. doi: 10.1097/00001721-199510000-00010.

DOI:10.1097/00001721-199510000-00010
PMID:8562841
Abstract

Acquired haemophilia is a rare disorder that it is associated with several diseases. Patients may present with spontaneous haematomas in different places which can sometimes be fatal. We present a 69-year-old woman with breast carcinoma who developed a factor VIII inhibitor. The initial haemorrhagic event was a spontaneous deep muscular haematoma in the right leg mimicking a deep venous thrombosis. She was successfully treated with prednisone.

摘要

获得性血友病是一种罕见的疾病,与多种疾病相关。患者可能会在不同部位出现自发性血肿,有时可能会致命。我们报告一名69岁患有乳腺癌的女性,她出现了Ⅷ因子抑制物。最初的出血事件是右下肢自发性深部肌肉血肿,类似深静脉血栓形成。她接受泼尼松治疗后获得成功。

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Presentation of an acquired factor VIII inhibitor with a muscular haematoma mimicking a deep venous thrombosis in a patient with breast cancer.一名乳腺癌患者出现获得性凝血因子VIII抑制剂,伴有模拟深静脉血栓形成的肌肉血肿。
Blood Coagul Fibrinolysis. 1995 Oct;6(7):680-2. doi: 10.1097/00001721-199510000-00010.
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Acquired factor VIII:C inhibitor in a patient with Sjögren's syndrome: successful treatment with steroid and immunosuppressive therapy.干燥综合征患者获得性凝血因子VIII:C抑制剂:类固醇和免疫抑制治疗成功案例
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Calf haematoma: a new sign in differential diagnosis from deep vein thrombosis.小腿血肿:鉴别诊断深静脉血栓形成的一个新体征。
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Acquired hemophilia secondary to factor VIII inhibitors after pregnancy.妊娠后继发于VIII因子抑制剂的获得性血友病
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A patient with acquired haemophilia A and pemphigus.一名患有获得性血友病A和天疱疮的患者。
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Acquired Haemophilia A: A Review of What We Know.获得性血友病A:我们所了解的综述。
J Blood Med. 2022 Nov 23;13:691-710. doi: 10.2147/JBM.S342077. eCollection 2022.