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沙利度胺对儿童的评估。 (注:原文“Evalulation”拼写错误,正确应为“Evaluation” )

Evalulation of thalidomide children.

作者信息

Ruffing L

出版信息

Birth Defects Orig Artic Ser. 1977;13(1):287-300.

PMID:856326
Abstract

All children suffering from thalidomide embryopathy should undergo a careful clinical and radiographic follow-up examination. This frequently detects hidden defects, especially of the spine and hip joints. It is clear that defects are frequently present, though unsuspected by the clinical examination. A special problem which needs further investigation is the alteration of the knee joints, which has also often been overlooked; Early osteoarthritis is expected to occur in the future. There is an urgent need for additional study of the general functional capacity and also the manual efficiency of the children under consideration for their occupational integration. We shall be engaged with this problem in future studies.

摘要

所有患有沙利度胺胚胎病的儿童都应接受仔细的临床和影像学随访检查。这常常能发现隐藏的缺陷,尤其是脊柱和髋关节的缺陷。很明显,尽管临床检查未察觉,但缺陷经常存在。一个需要进一步研究的特殊问题是膝关节的改变,这也常常被忽视;预计未来会出现早期骨关节炎。迫切需要对这些儿童的总体功能能力以及为使其融入职业而考虑的手部操作效率进行更多研究。我们将在未来的研究中关注这个问题。

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