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[前列腺慢性炎症条件下家兔肾上腺皮质的功能和结构变化]

[Functional and structural changes in the adrenal cortex of rabbits under conditions of chronic inflammation of the prostate gland].

作者信息

Aleshin B V, Bondarenko L A, Breslavskiĭ A S, Vartapetov B A, Gladkova A I

出版信息

Biull Eksp Biol Med. 1977 Mar;83(3):276-7.

PMID:856350
Abstract

Investigation of the state of the rabbit adrenal cortex under conditions of depression of the incretory activity of the testicles resulting from chronic inflammation of the prostate showed progressive hyperplasia of the reticular zone of the adrenal cortex; as to the glomerular zone, it failed to display any marked pathological changes, and the fascicular zone demonstrated some signs of hypoplasia. Thus, the normal or elevated androgen excretion observed in the experimental male rabbits, was provided by an intensified activity of the reticular zone of the adrenal cortex, despite a decrease in testosterone biosynthesis in the testes.

摘要

对因前列腺慢性炎症导致睾丸分泌活动受抑制情况下的兔肾上腺皮质状态进行的研究表明,肾上腺皮质网状带出现进行性增生;至于肾小球带,未显示出任何明显的病理变化,而束状带则表现出一些发育不全的迹象。因此,尽管实验雄兔睾丸中睾酮生物合成减少,但实验雄兔中观察到的正常或升高的雄激素排泄是由肾上腺皮质网状带活动增强所致。

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