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[长期运动减少对大鼠雄激素系统的影响]

[Effect of long-term hypokinesia on the androgenic system in rats].

作者信息

Kirillov O I, Kurilenko L A

出版信息

Kosm Biol Aviakosm Med. 1988 Jul-Aug;22(4):74-6.

PMID:3226099
Abstract

Rats were immobilized in small cages for 1, 5, 10, 15, 20, 30, 45, 60 or 90 days. After exposure the weight of testes, seminal vesicles and prostate as well as the volume of cell nuclei of the reticular area of the adrenal cortex was measured. The weight of seminal vesicles and prostate diminished 1.5-2 times while that of testes decreased insignificantly. Cell nuclei of the reticular area of the adrenal cortex were enlarged during the first 5 days of hypokinesia, returning to the baseline thereafter. Cell nuclei became less than the baseline after 20 days of hypokinesia. These changes in the reticular area were associated with secretion of glucocorticoids rather than androgens.

摘要

将大鼠置于小笼中固定1、5、10、15、20、30、45、60或90天。暴露后,测量睾丸、精囊和前列腺的重量以及肾上腺皮质网状区细胞核的体积。精囊和前列腺的重量减少了1.5 - 2倍,而睾丸重量的减少不显著。肾上腺皮质网状区的细胞核在运动减少的前5天增大,此后恢复到基线水平。运动减少20天后,细胞核小于基线水平。网状区的这些变化与糖皮质激素而非雄激素的分泌有关。

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Kosm Biol Aviakosm Med. 1988 Jul-Aug;22(4):74-6.
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